The average ragdoll cat lives between 12 and 17 years. Like many large breed cats, ragdoll cats are prone to some health conditions, including:

Weight issues:^{3Obesity in Cats. VCA Animal Hospitals.} While chubby cats might be cute, they’re not healthy. Ragdolls that are overweight or obese are prone to health issues, such as arthritis and diabetes. It’s important to keep your eye on a ragdoll’s weight; they are big cats to begin with and their fluffy fur may hide weight gain.
Bladder stones: These are very painful for cats, and symptoms can include blood in the urine. Other signs include vocalizing (crying) in the litter box, straining to urinate, or urinating outside the litter box.⁴ You can help your kitty avoid bladder stones and other urinary infections by encouraging them to drink lots of fresh water and scheduling regular checkups with their veterinarian.
Hypertrophic cardiomyopathy: HCM is a heart disease that causes thickening of the heart muscle. An echocardiogram can help diagnose the problem but only after the cat has developed HCM. Genetic testing can also help breeders avoid breeding cats with HCM, but it’s always a risk, and there is no cure once a cat develops HCM.